Chromosome 21-derived MicroRNAs Provide an Etiological Basis for Aberrant Protein Expression in Human Down Syndrome Brains

Down syndrome (DS), or Trisomy 21, is the most common genetic cause of cognitive impairment and congenital heart defects in the human population. Bioinformatic annotation has established that human chromosome 21 (Hsa21) harbors five microRNA (miRNAs) genes: miR-99a, let-7c, miR-125b-2, miR-155, and...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kuhn, Donald E., Nuovo, Gerard J., Terry, Alvin V., Martin, Mickey M., Malana, Geraldine E., Sansom, Sarah E., Pleister, Adam P., Beck, Wayne D., Head, Elizabeth, Feldman, David S., Elton, Terry S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
RNA-Mediated Regulation and Noncoding RNAs
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801278/
https://ncbi.nlm.nih.gov/pubmed/19897480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.033407
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares