Down-regulation of Micro-RNA-1 (miR-1) in Lung Cancer: SUPPRESSION OF TUMORIGENIC PROPERTY OF LUNG CANCER CELLS AND THEIR SENSITIZATION TO DOXORUBICIN-INDUCED APOPTOSIS BY miR-1

Micro-RNAs are ∼21–25-nucleotide-long noncoding RNAs that regulate gene expression primarily at the post-transcriptional level in animals. Here, we report that micro-RNA-1 (miR-1), abundant in the cardiac and smooth muscles, is expressed in the lung and is down-regulated in human primary lung cancer...

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Detalhes bibliográficos
Principais autores: Nasser, Mohd W., Datta, Jharna, Nuovo, Gerard, Kutay, Huban, Motiwala, Tasneem, Majumder, Sarmila, Wang, Bo, Suster, Saul, Jacob, Samson T., Ghoshal, Kalpana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
RNA-Mediated Regulation and Noncoding Rnas
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586284/
https://ncbi.nlm.nih.gov/pubmed/18818206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804788200
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