Human Chromosome 21-derived miRNAs are Over-expressed in Down Syndrome Brains and Hearts

Down syndrome (DS), or Trisomy 21, is the most common genetic cause of cognitive impairment and congenital heart defects in the human population. To date, the contribution of microRNAs (miRNAs) in DS has not been investigated. Bioinformatic analyses demonstrate that human chromosome 21 (Hsa21) harbo...

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Détails bibliographiques
Auteurs principaux: Kuhn, Donald E., Nuovo, Gerard J., Martin, Mickey M., Malana, Geraldine E., Pleister, Adam P., Jiang, Jinmai, Schmittgen, Thomas D., Terry, Alvin V., Gardiner, Katheleen, Head, Elizabeth, Feldman, David S., Elton, Terry S.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585520/
https://ncbi.nlm.nih.gov/pubmed/18387358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.03.120
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