Human Chromosome 21-derived miRNAs are Over-expressed in Down Syndrome Brains and Hearts

Down syndrome (DS), or Trisomy 21, is the most common genetic cause of cognitive impairment and congenital heart defects in the human population. To date, the contribution of microRNAs (miRNAs) in DS has not been investigated. Bioinformatic analyses demonstrate that human chromosome 21 (Hsa21) harbo...

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Detaylı Bibliyografya
Asıl Yazarlar: Kuhn, Donald E., Nuovo, Gerard J., Martin, Mickey M., Malana, Geraldine E., Pleister, Adam P., Jiang, Jinmai, Schmittgen, Thomas D., Terry, Alvin V., Gardiner, Katheleen, Head, Elizabeth, Feldman, David S., Elton, Terry S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585520/
https://ncbi.nlm.nih.gov/pubmed/18387358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.03.120
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