IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae

Pneumococcal lung infections represent a major cause of death worldwide. Single nucleotide polymorphisms (SNPs) in the NFKBIZ gene, encoding the transcription factor IκBζ, are associated with increased susceptibility to invasive pneumococcal disease. We hence analyzed how IκBζ might regulate inflamm...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sundaram, Kruthika, Rahman, Mohd. Akhlakur, Mitra, Srabani, Knoell, Daren L., Woodiga, Shireen A., King, Samantha J., Wewers, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012667/
https://ncbi.nlm.nih.gov/pubmed/27597997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161931
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