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Alpha 1-Antitrypsin Does Not Inhibit Human Monocyte Caspase-1

BACKGROUND: Alpha 1-antitrypsin (A1AT) is a 52 kDa serine protease inhibitor produced largely by hepatocytes but also by mononuclear phagocytes. A1AT chiefly inhibits neutrophil elastase and proteinase-3 but has also been reported to have immune modulatory functions including the ability to inhibit...

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Pubblicato in:PLoS One
Autori principali: Rahman, Mohd. Akhlakur, Mitra, Srabani, Sarkar, Anasuya, Wewers, Mark D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319913/
https://ncbi.nlm.nih.gov/pubmed/25658455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117330
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