Series Introduction: Replication-selective microbiological agents: fighting cancer with targeted germ warfare

Autor Kirn, David H.
Vydáno 2000

Redemption for the Field of Oncolytic Virotherapy

Autor Kirn, David H
Vydáno 2011

Replication-selective adenoviruses as oncolytic agents

Autor Heise, Carla, Kirn, David H.
Vydáno 2000

Intravascular adenoviral agents in cancer patients: Lessons from clinical trials

Autor Reid, Tony, Warren, Robert, Kirn, David
Vydáno v Cancer Gene Ther (2002)

Targeting of Interferon-Beta to Produce a Specific, Multi-Mechanistic Oncolytic Vaccinia Virus

Autor Kirn, David H, Wang, Yaohe, Le Boeuf, Fabrice, Bell, John, Thorne, Steve H
Vydáno 2007

The emerging therapeutic potential of the oncolytic immunotherapeutic Pexa-Vec (JX-594)

Autor Breitbach, Caroline J, Bell, John C, Hwang, Tae-Ho, Kirn, David H, Burke, James
Vydáno v Oncolytic Virother (2015)

Oncolytic virotherapy for advanced liver tumours

Autor Chang, Ju-Fang, Chen, Pei-Jer, Sze, Daniel Y, Reid, Tony, Bartlett, David, Kirn, David H, Liu, Ta-Chiang
Vydáno v J Cell Mol Med (2009)

Viral Vector Technologies and Strategies: Improving on Nature

Autor Croze, Roxanne H., Kotterman, Melissa, Burns, Christian H., Schmitt, Chris E., Quezada, Melissa, Schaffer, David, Kirn, David, Francis, Peter
Vydáno v Int Ophthalmol Clin (2021)

Quantification of RPE Changes in Choroideremia Using a Photoshop-Based Method

Autor Zhai, Yi, Xu, Manlong, Dimopoulos, Ioannis S., Birch, David G., Bernstein, Paul S., Holt, Jenny, Kirn, David, Francis, Peter, MacDonald, Ian M.
Vydáno v Transl Vis Sci Technol (2020)

Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963

Autor Thorne, Steve H., Hwang, Tae-Ho H., O’Gorman, William E., Bartlett, David L., Sei, Shizuko, Kanji, Femina, Brown, Christopher, Werier, Joel, Cho, Jin-Han, Lee, Dong-Ewon, Wang, Yaohe, Bell, John, Kirn, David H.
Vydáno 2007

Synergistic Interaction Between Oncolytic Viruses Augments Tumor Killing

Autor Le Boeuf, Fabrice, Diallo, Jean-Simon, McCart, J Andrea, Thorne, Steve, Falls, Theresa, Stanford, Marianne, Kanji, Femina, Auer, Rebecca, Brown, Christopher W, Lichty, Brian D, Parato, Kelley, Atkins, Harold, Kirn, David, Bell, John C
Vydáno 2010

A Mechanistic Proof-of-concept Clinical Trial With JX-594, a Targeted Multi-mechanistic Oncolytic Poxvirus, in Patients With Metastatic Melanoma

Autor Hwang, Tae-Ho, Moon, Anne, Burke, James, Ribas, Antoni, Stephenson, Joe, Breitbach, Caroline J, Daneshmand, Manijeh, De Silva, Naomi, Parato, Kelley, Diallo, Jean-Simon, Lee, Yeon-Sook, Liu, Ta-Chiang, Bell, John C, Kirn, David H
Vydáno 2011

Efficacy and Safety/Toxicity Study of Recombinant Vaccinia Virus JX-594 in Two Immunocompetent Animal Models of Glioma

Autor Lun, XueQing, Chan, Jennifer, Zhou, Hongyuan, Sun, Beichen, Kelly, John JP, Stechishin, Owen Owen, Bell, John C, Parato, Kelley, Hu, Kang, Vaillant, Dominique, Wang, Jiahu, Liu, Ta-Chiang, Breitbach, Caroline, Kirn, David, Senger, Donna L, Forsyth, Peter A
Vydáno 2010

Enhancement of Vaccinia Virus Based Oncolysis with Histone Deacetylase Inhibitors

Autor MacTavish, Heather, Diallo, Jean-Simon, Huang, Baocheng, Stanford, Marianne, Le Boeuf, Fabrice, De Silva, Naomi, Cox, Julie, Simmons, John Graydon, Guimond, Tanya, Falls, Theresa, McCart, J. Andrea, Atkins, Harry, Breitbach, Caroline, Kirn, David, Thorne, Stephen, Bell, John C.
Vydáno 2010

Targeting Tumor Vasculature With an Oncolytic Virus

Autor Breitbach, Caroline J, De Silva, Naomi S, Falls, Theresa J, Aladl, Usaf, Evgin, Laura, Paterson, Jennifer, Sun, Yang Yang, Roy, Dominic G, Rintoul, Julia L, Daneshmand, Manijeh, Parato, Kelley, Stanford, Marianne M, Lichty, Brian D, Fenster, Aaron, Kirn, David, Atkins, Harold, Bell, John C
Vydáno 2011

Phase 1 Study of Intratumoral Pexa-Vec (JX-594), an Oncolytic and Immunotherapeutic Vaccinia Virus, in Pediatric Cancer Patients

Autor Cripe, Timothy P, Ngo, Minhtran C, Geller, James I, Louis, Chrystal U, Currier, Mark A, Racadio, John M, Towbin, Alexander J, Rooney, Cliona M, Pelusio, Adina, Moon, Anne, Hwang, Tae-Ho, Burke, James M, Bell, John C, Kirn, David H, Breitbach, Caroline J
Vydáno v Mol Ther (2015)

Phase 1b Trial of Biweekly Intravenous Pexa-Vec (JX-594), an Oncolytic and Immunotherapeutic Vaccinia Virus in Colorectal Cancer

Autor Park, Se Hoon, Breitbach, Caroline J, Lee, Jeeyun, Park, Joon Oh, Lim, Ho Yeong, Kang, Won Ki, Moon, Anne, Mun, Jae-Hee, Sommermann, Erica M, Maruri Avidal, Liliana, Patt, Rick, Pelusio, Adina, Burke, James, Hwang, Tae-Ho, Kirn, David, Park, Young Suk
Vydáno v Mol Ther (2015)

Amplification of oncolytic vaccinia virus widespread tumor cell killing by sunitinib through multiple mechanisms

Autor Kim, Minah, Nitschké, Maximilian, Sennino, Barbara, Murer, Patrizia, Schriver, Brian J., Bell, Alexander, Subramanian, Aishwarya, McDonald, Corry E., Wang, Jiahu, Cha, Howard, Bourgeois-Daigneault, Marie-Claude, Kirn, David H., Bell, John C., De Silva, Naomi, Breitbach, Caroline J., McDonald, Donald M.
Vydáno v Cancer Res (2017)

A High-throughput Pharmacoviral Approach Identifies Novel Oncolytic Virus Sensitizers

Autor Diallo, Jean-Simon, Boeuf, Fabrice Le, Lai, Frances, Cox, Julie, Vaha-Koskela, Markus, Abdelbary, Hesham, MacTavish, Heather, Waite, Katherine, Falls, Theresa, Wang, Jenny, Brown, Ryan, Blanchard, Jan E, Brown, Eric D, Kirn, David H, Hiscott, John, Atkins, Harry, Lichty, Brian D, Bell, John C
Vydáno 2010

Sequential Therapy With JX-594, A Targeted Oncolytic Poxvirus, Followed by Sorafenib in Hepatocellular Carcinoma: Preclinical and Clinical Demonstration of Combination Efficacy

Autor Heo, Jeong, Breitbach, Caroline J, Moon, Anne, Kim, Chang Won, Patt, Rick, Kim, Mi Kyung, Lee, Yu Kyung, Oh, Sung Yong, Woo, Hyun Young, Parato, Kelley, Rintoul, Julia, Falls, Theresa, Hickman, Theresa, Rhee, Byung-Geon, Bell, John C, Kirn, David H, Hwang, Tae-Ho
Vydáno 2011