Enhancement of Vaccinia Virus Based Oncolysis with Histone Deacetylase Inhibitors

Histone deacetylase inhibitors (HDI) dampen cellular innate immune response by decreasing interferon production and have been shown to increase the growth of vesicular stomatitis virus and HSV. As attenuated tumour-selective oncolytic vaccinia viruses (VV) are already undergoing clinical evaluation,...

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Detalhes bibliográficos
Main Authors: MacTavish, Heather, Diallo, Jean-Simon, Huang, Baocheng, Stanford, Marianne, Le Boeuf, Fabrice, De Silva, Naomi, Cox, Julie, Simmons, John Graydon, Guimond, Tanya, Falls, Theresa, McCart, J. Andrea, Atkins, Harry, Breitbach, Caroline, Kirn, David, Thorne, Stephen, Bell, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012680/
https://ncbi.nlm.nih.gov/pubmed/21283510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014462
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