Enhancement of Vaccinia Virus Based Oncolysis with Histone Deacetylase Inhibitors

Histone deacetylase inhibitors (HDI) dampen cellular innate immune response by decreasing interferon production and have been shown to increase the growth of vesicular stomatitis virus and HSV. As attenuated tumour-selective oncolytic vaccinia viruses (VV) are already undergoing clinical evaluation,...

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Détails bibliographiques
Auteurs principaux: MacTavish, Heather, Diallo, Jean-Simon, Huang, Baocheng, Stanford, Marianne, Le Boeuf, Fabrice, De Silva, Naomi, Cox, Julie, Simmons, John Graydon, Guimond, Tanya, Falls, Theresa, McCart, J. Andrea, Atkins, Harry, Breitbach, Caroline, Kirn, David, Thorne, Stephen, Bell, John C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012680/
https://ncbi.nlm.nih.gov/pubmed/21283510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014462
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