Synergistic Interaction Between Oncolytic Viruses Augments Tumor Killing

A major barrier to all oncolytic viruses (OVs) in clinical development is cellular innate immunity, which is variably active in a spectrum of human malignancies. To overcome the heterogeneity of tumor response, we combined complementary OVs that attack cancers in distinct ways to improve therapeutic...

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Detalhes bibliográficos
Main Authors: Le Boeuf, Fabrice, Diallo, Jean-Simon, McCart, J Andrea, Thorne, Steve, Falls, Theresa, Stanford, Marianne, Kanji, Femina, Auer, Rebecca, Brown, Christopher W, Lichty, Brian D, Parato, Kelley, Atkins, Harold, Kirn, David, Bell, John C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890112/
https://ncbi.nlm.nih.gov/pubmed/20234341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.44
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