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The emerging therapeutic potential of the oncolytic immunotherapeutic Pexa-Vec (JX-594)

Oncolytic immunotherapeutics (OIs) are viruses designed to preferentially replicate in and lyse cancer cells, thereby triggering antitumor immunity. Numerous oncolytic platforms are currently in clinical development. Here we review preclinical and clinical experience with Pexa-Vec (pexastimogene dev...

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Bibliografske podrobnosti
izdano v:Oncolytic Virother
Main Authors: Breitbach, Caroline J, Bell, John C, Hwang, Tae-Ho, Kirn, David H, Burke, James
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918374/
https://ncbi.nlm.nih.gov/pubmed/27512667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S59640
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