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The emerging therapeutic potential of the oncolytic immunotherapeutic Pexa-Vec (JX-594)
Oncolytic immunotherapeutics (OIs) are viruses designed to preferentially replicate in and lyse cancer cells, thereby triggering antitumor immunity. Numerous oncolytic platforms are currently in clinical development. Here we review preclinical and clinical experience with Pexa-Vec (pexastimogene dev...
Gespeichert in:
| Veröffentlicht in: | Oncolytic Virother |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918374/ https://ncbi.nlm.nih.gov/pubmed/27512667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S59640 |
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