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The emerging therapeutic potential of the oncolytic immunotherapeutic Pexa-Vec (JX-594)
Oncolytic immunotherapeutics (OIs) are viruses designed to preferentially replicate in and lyse cancer cells, thereby triggering antitumor immunity. Numerous oncolytic platforms are currently in clinical development. Here we review preclinical and clinical experience with Pexa-Vec (pexastimogene dev...
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| 發表在: | Oncolytic Virother |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Dove Medical Press
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918374/ https://ncbi.nlm.nih.gov/pubmed/27512667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S59640 |
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