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A High-throughput Pharmacoviral Approach Identifies Novel Oncolytic Virus Sensitizers

Oncolytic viruses (OVs) are promising anticancer agents but like other cancer monotherapies, the genetic heterogeneity of human malignancies can lead to treatment resistance. We used a virus/cell-based assay to screen diverse chemical libraries to identify small molecules that could act in synergy w...

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מידע ביבליוגרפי
Main Authors: Diallo, Jean-Simon, Boeuf, Fabrice Le, Lai, Frances, Cox, Julie, Vaha-Koskela, Markus, Abdelbary, Hesham, MacTavish, Heather, Waite, Katherine, Falls, Theresa, Wang, Jenny, Brown, Ryan, Blanchard, Jan E, Brown, Eric D, Kirn, David H, Hiscott, John, Atkins, Harry, Lichty, Brian D, Bell, John C
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889739/
https://ncbi.nlm.nih.gov/pubmed/20389287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.67
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