A High-throughput Pharmacoviral Approach Identifies Novel Oncolytic Virus Sensitizers

Oncolytic viruses (OVs) are promising anticancer agents but like other cancer monotherapies, the genetic heterogeneity of human malignancies can lead to treatment resistance. We used a virus/cell-based assay to screen diverse chemical libraries to identify small molecules that could act in synergy w...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Diallo, Jean-Simon, Boeuf, Fabrice Le, Lai, Frances, Cox, Julie, Vaha-Koskela, Markus, Abdelbary, Hesham, MacTavish, Heather, Waite, Katherine, Falls, Theresa, Wang, Jenny, Brown, Ryan, Blanchard, Jan E, Brown, Eric D, Kirn, David H, Hiscott, John, Atkins, Harry, Lichty, Brian D, Bell, John C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889739/
https://ncbi.nlm.nih.gov/pubmed/20389287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.67
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky