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Bacterial-Mediated Knockdown of Tumor Resistance to an Oncolytic Virus Enhances Therapy

Oncolytic viruses (OVs) and bacteria share the property of tumor-selective replication following systemic administration. In the case of nonpathogenic bacteria, tumor selectivity relates to their ability to grow extracellularly within tumor stroma and is therefore ideally suited to restricting the p...

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Detalhes bibliográficos
Main Authors: Cronin, Michelle, Le Boeuf, Fabrice, Murphy, Carola, Roy, Dominic G, Falls, Theresa, Bell, John C, Tangney, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048890/
https://ncbi.nlm.nih.gov/pubmed/24569832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.23
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