Bacterial-Mediated Knockdown of Tumor Resistance to an Oncolytic Virus Enhances Therapy

Oncolytic viruses (OVs) and bacteria share the property of tumor-selective replication following systemic administration. In the case of nonpathogenic bacteria, tumor selectivity relates to their ability to grow extracellularly within tumor stroma and is therefore ideally suited to restricting the p...

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Autors principals: Cronin, Michelle, Le Boeuf, Fabrice, Murphy, Carola, Roy, Dominic G, Falls, Theresa, Bell, John C, Tangney, Mark
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048890/
https://ncbi.nlm.nih.gov/pubmed/24569832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.23
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