Reovirus FAST Protein Enhances Vesicular Stomatitis Virus Oncolytic Virotherapy in Primary and Metastatic Tumor Models

The reovirus fusion-associated small transmembrane (FAST) proteins are the smallest known viral fusogens (∼100–150 amino acids) and efficiently induce cell-cell fusion and syncytium formation in multiple cell types. Syncytium formation enhances cell-cell virus transmission and may also induce immuno...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Oncolytics
Hauptverfasser: Le Boeuf, Fabrice, Gebremeskel, Simon, McMullen, Nichole, He, Han, Greenshields, Anna L., Hoskin, David W., Bell, John C., Johnston, Brent, Pan, Chungen, Duncan, Roy
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562180/
https://ncbi.nlm.nih.gov/pubmed/28856238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2017.08.001
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