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Mutations in the Glycoprotein of Vesicular Stomatitis Virus Affect Cytopathogenicity: Potential for Oncolytic Virotherapy

Vesicular stomatitis virus (VSV) has been widely used to characterize cellular processes, viral resistance, and cytopathogenicity. Recently, VSV has also been used for oncolytic virotherapy due to its capacity to selectively lyse tumor cells. Mutants of the matrix (M) protein of VSV have generally b...

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Detalhes bibliográficos
Main Authors: Janelle, Valérie, Brassard, Frédérick, Lapierre, Pascal, Lamarre, Alain, Poliquin, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126483/
https://ncbi.nlm.nih.gov/pubmed/21561919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02484-10
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