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Mutations in the Glycoprotein of Vesicular Stomatitis Virus Affect Cytopathogenicity: Potential for Oncolytic Virotherapy

Vesicular stomatitis virus (VSV) has been widely used to characterize cellular processes, viral resistance, and cytopathogenicity. Recently, VSV has also been used for oncolytic virotherapy due to its capacity to selectively lyse tumor cells. Mutants of the matrix (M) protein of VSV have generally b...

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Main Authors: Janelle, Valérie, Brassard, Frédérick, Lapierre, Pascal, Lamarre, Alain, Poliquin, Laurent
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126483/
https://ncbi.nlm.nih.gov/pubmed/21561919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02484-10
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