Drugs acting on central nervous system (CNS) targets as leads for non-CNS targets

Tekijä Kharkar, Prashant S.
Julkaistu 2014

Newer human inosine 5′-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents

Tekijä Shah, Chetan P., Kharkar, Prashant S.
Julkaisussa J Enzyme Inhib Med Chem (2018)

Understanding the Structural Requirements of Hybrid (S)-6-((2-(4-Phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol and its Analogs as D2/D3 Receptor Ligan...

Tekijä Modi, Gyan, Sharma, Horrick, Kharkar, Prashant S., Dutta, Aloke K.
Julkaistu 2014

Crocetin and related oxygen diffusion‐enhancing compounds: Review of chemical synthesis, pharmacology, clinical development, and novel therapeutic applications

Tekijä Shah, Hriday M., Jain, Ashvi S., Joshi, Shreerang V., Kharkar, Prashant S.
Julkaisussa Drug Dev Res (2021)

Carbonic Anhydrase Inhibitors: Design, Synthesis, and Biological Evaluation of Novel Sulfonyl Semicarbazide Derivatives

Tekijä Pichake, Jayashree, Kharkar, Prashant S., Ceruso, Mariangela, Supuran, Claudiu T., Toraskar, Mrunmayee P.
Julkaistu 2014

Modification of agonist binding moiety in hybrid derivative 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-1-ol/-2-amino versions: Impact on fun...

Tekijä Gopishetty, Bhaskar, Zhang, Suhong, Kharkar, Prashant S., Antonio, Tamara, Reith, Maarten, Dutta, Aloke K.
Julkaistu 2013

Structurally constrained hybrid derivatives containing octahydrobenzo[g or f]quinoline moieties for dopamine D2 and D3 receptors: Binding characterization at D2/D3 receptors and el...

Tekijä Brown, Dennis A., Kharkar, Prashant S., Parrington, Ingrid, Reith, Maarten E.A., Dutta, Aloke K.
Julkaistu 2008

Development of (S)-N(6)-(2-(4-(Isoquinolin-1-yl)piperazin-1-yl)ethyl)-N(6)-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agoni...

Tekijä Ghosh, Balaram, Antonio, Tamara, Zhen, Juan, Kharkar, Prashant, Reith, Maarten E. A., Dutta, Aloke K.
Julkaistu 2010

Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for monoamine transporters

Tekijä Kharkar, Prashant S., Batman, Angela M., Zhen, Juan, Beardsley, Patrick M., Reith, Maarten E. A., Dutta, Aloke K.
Julkaistu 2009

Attenuation of quorum sensing-regulated behaviour by Tinospora cordifolia extract & identification of its active constituents

Tekijä Gala, Viraj C., John, Nithya R., Bhagwat, Ashok M., Datar, Ajit G., Kharkar, Prashant S., Desai, Krutika B.
Julkaisussa Indian J Med Res (2016)

INTERACTION OF COCAINE-, BENZTROPINE-, AND GBR12909-LIKE COMPOUNDS WITH WILDTYPE AND MUTANT HUMAN DOPAMINE TRANSPORTERS: MOLECULAR FEATURES THAT DIFFERENTIALLY DETERMINE ANTAGONIST...

Tekijä Schmitt, Kyle C., Zhen, Juan, Kharkar, Prashant, Mishra, Manoj, Chen, Nianhang, Dutta, Aloke K., Reith, Maarten E.A.
Julkaistu 2008