Newer human inosine 5′-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents

Human inosine 5′-monophosphate dehydrogenase 2 (hIMPDH2), being an age-old target, has attracted attention recently for anticancer drug development. Mycophenolic acid (MPA), a well-known immunosuppressant drug, was used a lead structure to design and develop modestly potent and selective analogues....

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Vydáno v:J Enzyme Inhib Med Chem
Hlavní autoři: Shah, Chetan P., Kharkar, Prashant S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Short Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009919/
https://ncbi.nlm.nih.gov/pubmed/29792360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1474211
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