Drugs acting on central nervous system (CNS) targets as leads for non-CNS targets

Por Kharkar, Prashant S.
Publicado em 2014

Newer human inosine 5′-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents

Por Shah, Chetan P., Kharkar, Prashant S.
Publicado no J Enzyme Inhib Med Chem (2018)

Understanding the Structural Requirements of Hybrid (S)-6-((2-(4-Phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol and its Analogs as D2/D3 Receptor Ligan...

Por Modi, Gyan, Sharma, Horrick, Kharkar, Prashant S., Dutta, Aloke K.
Publicado em 2014

Carbonic Anhydrase Inhibitors: Design, Synthesis, and Biological Evaluation of Novel Sulfonyl Semicarbazide Derivatives

Por Pichake, Jayashree, Kharkar, Prashant S., Ceruso, Mariangela, Supuran, Claudiu T., Toraskar, Mrunmayee P.
Publicado em 2014

Modification of agonist binding moiety in hybrid derivative 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-1-ol/-2-amino versions: Impact on fun...

Por Gopishetty, Bhaskar, Zhang, Suhong, Kharkar, Prashant S., Antonio, Tamara, Reith, Maarten, Dutta, Aloke K.
Publicado em 2013

Structurally constrained hybrid derivatives containing octahydrobenzo[g or f]quinoline moieties for dopamine D2 and D3 receptors: Binding characterization at D2/D3 receptors and el...

Por Brown, Dennis A., Kharkar, Prashant S., Parrington, Ingrid, Reith, Maarten E.A., Dutta, Aloke K.
Publicado em 2008

Development of (S)-N(6)-(2-(4-(Isoquinolin-1-yl)piperazin-1-yl)ethyl)-N(6)-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agoni...

Por Ghosh, Balaram, Antonio, Tamara, Zhen, Juan, Kharkar, Prashant, Reith, Maarten E. A., Dutta, Aloke K.
Publicado em 2010

Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for monoamine transporters

Por Kharkar, Prashant S., Batman, Angela M., Zhen, Juan, Beardsley, Patrick M., Reith, Maarten E. A., Dutta, Aloke K.
Publicado em 2009

Attenuation of quorum sensing-regulated behaviour by Tinospora cordifolia extract & identification of its active constituents

Por Gala, Viraj C., John, Nithya R., Bhagwat, Ashok M., Datar, Ajit G., Kharkar, Prashant S., Desai, Krutika B.
Publicado no Indian J Med Res (2016)

INTERACTION OF COCAINE-, BENZTROPINE-, AND GBR12909-LIKE COMPOUNDS WITH WILDTYPE AND MUTANT HUMAN DOPAMINE TRANSPORTERS: MOLECULAR FEATURES THAT DIFFERENTIALLY DETERMINE ANTAGONIST...

Por Schmitt, Kyle C., Zhen, Juan, Kharkar, Prashant, Mishra, Manoj, Chen, Nianhang, Dutta, Aloke K., Reith, Maarten E.A.
Publicado em 2008