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Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for monoamine transporters

In this report we describe synthesis and biological evaluation of a series of asymmetric 4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol based dihydroxy compounds where the hydroxy groups are located both on the piperidine ring and also on the N-phenylethyl side chain exo-c...

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Detalhes bibliográficos
Main Authors: Kharkar, Prashant S., Batman, Angela M., Zhen, Juan, Beardsley, Patrick M., Reith, Maarten E. A., Dutta, Aloke K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517155/
https://ncbi.nlm.nih.gov/pubmed/19449323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.200900085
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