OUR CELLS GET STRESSED TOO! IMPLICATIONS FOR HUMAN DISEASE

Por Kastan, Michael B.
Publicado em 2007

5′–3′-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage

Por Chen, Jing, Kastan, Michael B.
Publicado em 2010

Repair versus checkpoint functions of Brca1 are differentially regulated by site of chromatin binding

Por Goldstein, Michael, Kastan, Michael B.
Publicado no Cancer Res (2015)

A novel DNA damage-induced alternative splicing pathway that regulates p53 and cellular senescence markers

Por Chen, Jing, Kastan, Michael B.
Publicado no Oncoscience (2017)

Multiple roles of atm in monitoring and maintaining dna integrity

Por Derheimer, Frederick A, Kastan, Michael B
Publicado em 2010

Chromatin perturbations during the DNA damage response in higher eukaryotes

Por Bakkenist, Christopher J., Kastan, Michael B.
Publicado no DNA Repair (Amst) (2015)

Interactions of Nucleolin and Ribosomal Protein L26 (RPL26) in Translational Control of Human p53 mRNA

Por Chen, Jing, Guo, Kexiao, Kastan, Michael B.
Publicado em 2012

A new role for ATM: Regulating mitochondrial function and mitophagy

Por Valentin-Vega, Yasmine A., Kastan, Michael B.
Publicado em 2012

Involvement of Brca1 in S-Phase and G(2)-Phase Checkpoints after Ionizing Irradiation

Por Xu, Bo, Kim, Seong-tae, Kastan, Michael B.
Publicado em 2001

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

Por Kim, Seong-Tae, Xu, Bo, Kastan, Michael B.
Publicado em 2002

NAD(+) Modulates p53 DNA Binding Specificity and Function

Por McLure, Kevin G., Takagi, Masatoshi, Kastan, Michael B.
Publicado em 2004

Strategies for optimizing the response of cancer and normal tissues to radiation

Por Moding, Everett J., Kastan, Michael B., Kirsch, David G.
Publicado em 2013

Two Molecularly Distinct G(2)/M Checkpoints Are Induced by Ionizing Irradiation

Por Xu, Bo, Kim, Seong-Tae, Lim, Dae-Sik, Kastan, Michael B.
Publicado em 2002

Nucleolin mediates nucleosome disruption critical for DNA double-strand break repair

Por Goldstein, Michael, Derheimer, Frederick A., Tait-Mulder, Jacqueline, Kastan, Michael B.
Publicado em 2013

IDENTIFICATION A DNA DAMAGE-INDUCED ALTERNATIVE SPLICING PATHWAY THAT REGULATES p53 AND CELLULAR SENESCENCE MARKERS

Por Chen, Jing, Crutchley, John, Zhang, Dadong, Owzar, Kouros, Kastan, Michael B.
Publicado no Cancer Discov (2017)

Phosphorylation of SMC1 is a critical downstream event in the ATM–NBS1–BRCA1 pathway

Por Kitagawa, Risa, Bakkenist, Christopher J., McKinnon, Peter J., Kastan, Michael B.
Publicado em 2004

Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis

Por Maclean, Kirsteen H., Dorsey, Frank C., Cleveland, John L., Kastan, Michael B.
Publicado em 2007

Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis

Por Maclean, Kirsteen H., Dorsey, Frank C., Cleveland, John L., Kastan, Michael B.
Publicado em 2008

Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to Ionizing Radiation

Por Rainey, Michael D., Charlton, Maura E., Stanton, Robert V., Kastan, Michael B.
Publicado em 2008

Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26

Por Ofir-Rosenfeld, Yaara, Boggs, Kristy, Michael, Dan, Kastan, Michael B., Oren, Moshe
Publicado em 2008