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Phosphorylation of SMC1 is a critical downstream event in the ATM–NBS1–BRCA1 pathway

The ATM protein kinase is activated by intermolecular autophosphorylation in response to DNA damage and initiates cellular signaling pathways that facilitate cell survival and reduce chromosomal breakage. Here, we show that NBS1 and BRCA1 are required for the recruitment of previously activated ATM...

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Bibliografski detalji
Glavni autori: Kitagawa, Risa, Bakkenist, Christopher J., McKinnon, Peter J., Kastan, Michael B.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC423193/
https://ncbi.nlm.nih.gov/pubmed/15175241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1200304
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