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Phosphorylation of SMC1 is a critical downstream event in the ATM–NBS1–BRCA1 pathway
The ATM protein kinase is activated by intermolecular autophosphorylation in response to DNA damage and initiates cellular signaling pathways that facilitate cell survival and reduce chromosomal breakage. Here, we show that NBS1 and BRCA1 are required for the recruitment of previously activated ATM...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC423193/ https://ncbi.nlm.nih.gov/pubmed/15175241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1200304 |
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