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Phosphorylation of SMC1 is a critical downstream event in the ATM–NBS1–BRCA1 pathway

The ATM protein kinase is activated by intermolecular autophosphorylation in response to DNA damage and initiates cellular signaling pathways that facilitate cell survival and reduce chromosomal breakage. Here, we show that NBS1 and BRCA1 are required for the recruitment of previously activated ATM...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kitagawa, Risa, Bakkenist, Christopher J., McKinnon, Peter J., Kastan, Michael B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2004
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC423193/
https://ncbi.nlm.nih.gov/pubmed/15175241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1200304
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