A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein

BRCA1 is a central component of the DNA damage response mechanism and defects in BRCA1 confer sensitivity to a broad range of DNA damaging agents. BRCA1 is required for homologous recombination and DNA damage-induced S and G(2)/M phase arrest. We show here that BRCA1 is required for ATM- and ATR-dep...

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Détails bibliographiques
Auteurs principaux: Foray, Nicolas, Marot, Didier, Gabriel, Anastasia, Randrianarison, Voahangy, Carr, Antony M., Perricaudet, Michel, Ashworth, Alan, Jeggo, Penny
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2003
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC156770/
https://ncbi.nlm.nih.gov/pubmed/12773400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg274
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