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A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein
BRCA1 is a central component of the DNA damage response mechanism and defects in BRCA1 confer sensitivity to a broad range of DNA damaging agents. BRCA1 is required for homologous recombination and DNA damage-induced S and G(2)/M phase arrest. We show here that BRCA1 is required for ATM- and ATR-dep...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156770/ https://ncbi.nlm.nih.gov/pubmed/12773400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg274 |
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