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ATM/ATR‐mediated phosphorylation of PALB2 promotes RAD51 function
DNA damage activates the ATM and ATR kinases that coordinate checkpoint and DNA repair pathways. An essential step in homology‐directed repair (HDR) of DNA breaks is the formation of RAD51 nucleofilaments mediated by PALB2–BRCA2; however, roles of ATM and ATR in this critical step of HDR are poorly...
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| 出版年: | EMBO Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341514/ https://ncbi.nlm.nih.gov/pubmed/27113759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541455 |
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