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ATM/ATR‐mediated phosphorylation of PALB2 promotes RAD51 function
DNA damage activates the ATM and ATR kinases that coordinate checkpoint and DNA repair pathways. An essential step in homology‐directed repair (HDR) of DNA breaks is the formation of RAD51 nucleofilaments mediated by PALB2–BRCA2; however, roles of ATM and ATR in this critical step of HDR are poorly...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341514/ https://ncbi.nlm.nih.gov/pubmed/27113759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541455 |
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