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A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein
BRCA1 is a central component of the DNA damage response mechanism and defects in BRCA1 confer sensitivity to a broad range of DNA damaging agents. BRCA1 is required for homologous recombination and DNA damage-induced S and G(2)/M phase arrest. We show here that BRCA1 is required for ATM- and ATR-dep...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156770/ https://ncbi.nlm.nih.gov/pubmed/12773400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg274 |
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