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Repair versus checkpoint functions of Brca1 are differentially regulated by site of chromatin binding
The product of the Brca1 tumor-suppressor gene is involved in multiple aspects of the cellular DNA damage response (DDR), including activation of cell cycle arrests and DNA double-stranded break (DSB) repair by homologous recombination (HR). Prior reports demonstrated that Brca1 recruitment to areas...
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| Publicado no: | Cancer Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4548823/ https://ncbi.nlm.nih.gov/pubmed/25939603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0400 |
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