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A new role for ATM: Regulating mitochondrial function and mitophagy
The various pathologies in ataxia telangiectasia (A-T) patients including T-cell lymphomagenesis have been attributed to defects in the DNA damage response pathway because ATM, the gene mutated in this disease, is a key mediator of this process. Analysis of Atm-deficient thymocytes in mice reveals t...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679088/ https://ncbi.nlm.nih.gov/pubmed/22617444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19693 |
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