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IDENTIFICATION A DNA DAMAGE-INDUCED ALTERNATIVE SPLICING PATHWAY THAT REGULATES p53 AND CELLULAR SENESCENCE MARKERS
Cellular responses to DNA damage are critical determinants of cancer development and aging-associated pathogenesis. Here we report a novel DNA damage response pathway that regulates alternative splicing of numerous gene products, including the human tumor suppressor p53, and controls DNA damage-indu...
Gespeichert in:
| Veröffentlicht in: | Cancer Discov |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501752/ https://ncbi.nlm.nih.gov/pubmed/28288992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0908 |
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