Peroxisome proliferator-activated receptor-α expression induces alterations in cardiac myofilaments in a pressure-overload model of hypertrophy

Por Karam, Chehade N., Warren, Chad M., Henze, Marcus, Banke, Natasha H., Lewandowski, E. Douglas, Solaro, R. John
Publicado no Am J Physiol Heart Circ Physiol (2017)

Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyos...

Por Karam, Chehade N., Warren, Chad M., Rajan, Sudarsan, de Tombe, Pieter P., Wieczorek, David F., Solaro, R. John
Publicado em 2011

Absence of physiological Ca(2+) transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation

Por Karam, Chehade, Yi, Jianxun, Xiao, Yajuan, Dhakal, Kamal, Zhang, Lin, Li, Xuejun, Manno, Carlo, Xu, Jiejia, Li, Kaitao, Cheng, Heping, Ma, Jianjie, Zhou, Jingsong
Publicado no Skelet Muscle (2017)

ROS-related Mitochondrial Dysfunction in Skeletal Muscle of an ALS Mouse Model during the Disease Progression

Por Xiao, Yajuan, Karam, Chehade, Yi, Jianxun, Zhang, Lin, Li, Xuejun, Yoon, Dosuk, Wang, Huan, Dhakal, Kamal, Ramlow, Paul, Yu, Tian, Mo, Zhaohui, Ma, Jianjie, Zhou, Jingsong
Publicado no Pharmacol Res (2018)

A Green Tea Catechin Normalizes the Enhanced Ca(2+) Sensitivity of Myofilaments Regulated by a Hypertrophic Cardiomyopathy Associated Mutation in Human Cardiac Troponin I (K206I)

Por Warren, Chad M., Karam, Chehade N., Wolska, Beata M., Kobayashi, Tomoyoshi, de Tombe, Pieter P., Arteaga, Grace M., Bos, J. Martijn, Ackerman, Michael J., Solaro, R. John
Publicado no Circ Cardiovasc Genet (2015)

Molecular and Functional Characterization of a Novel Cardiac Specific Human Tropomyosin Isoform

Por Rajan, Sudarsan, Jagatheesan, Ganapathy, Karam, Chehade N., Alves, Marco L., Bodi, Ilona, Schwartz, Arnold, Bulcao, Christian F., D'Souza, Karen M., Akhter, Shahab A., Boivin, Greg P., Dube, Dipak K., Petrashevskaya, Natalia, Herr, Andrew B., Hullin, Roger, Liggett, Stephen B., Wolska, Beata M., Solaro, R. John, Wieczorek, David F.
Publicado em 2010