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ROS-related Mitochondrial Dysfunction in Skeletal Muscle of an ALS Mouse Model during the Disease Progression
In amyotrophic lateral sclerosis (ALS), mitochondrial dysfunction and oxidative stress form a vicious cycle that promotes neurodegeneration and muscle wasting. To quantify the diseasestage-dependent changes of mitochondrial function and their relationship to the generation of reactive oxygen species...
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發表在: | Pharmacol Res |
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Main Authors: | , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
2018
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6263743/ https://ncbi.nlm.nih.gov/pubmed/30236524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2018.09.008 |
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