ROS-related Mitochondrial Dysfunction in Skeletal Muscle of an ALS Mouse Model during the Disease Progression

In amyotrophic lateral sclerosis (ALS), mitochondrial dysfunction and oxidative stress form a vicious cycle that promotes neurodegeneration and muscle wasting. To quantify the diseasestage-dependent changes of mitochondrial function and their relationship to the generation of reactive oxygen species...

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Veröffentlicht in:Pharmacol Res
Hauptverfasser: Xiao, Yajuan, Karam, Chehade, Yi, Jianxun, Zhang, Lin, Li, Xuejun, Yoon, Dosuk, Wang, Huan, Dhakal, Kamal, Ramlow, Paul, Yu, Tian, Mo, Zhaohui, Ma, Jianjie, Zhou, Jingsong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263743/
https://ncbi.nlm.nih.gov/pubmed/30236524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2018.09.008
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