Defective Mitochondrial Dynamics Is an Early Event in Skeletal Muscle of an Amyotrophic Lateral Sclerosis Mouse Model

Mitochondria are dynamic organelles that constantly undergo fusion and fission to maintain their normal functionality. Impairment of mitochondrial dynamics is implicated in various neurodegenerative disorders. Amyotrophic lateral sclerosis (ALS) is an adult-onset neuromuscular degenerative disorder...

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Bibliographic Details
Main Authors: Luo, Guo, Yi, Jianxun, Ma, Changling, Xiao, Yajuan, Yi, Frank, Yu, Tian, Zhou, Jingsong
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855744/
https://ncbi.nlm.nih.gov/pubmed/24324755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082112
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