Defective Mitochondrial Dynamics Is an Early Event in Skeletal Muscle of an Amyotrophic Lateral Sclerosis Mouse Model

Mitochondria are dynamic organelles that constantly undergo fusion and fission to maintain their normal functionality. Impairment of mitochondrial dynamics is implicated in various neurodegenerative disorders. Amyotrophic lateral sclerosis (ALS) is an adult-onset neuromuscular degenerative disorder...

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Autors principals: Luo, Guo, Yi, Jianxun, Ma, Changling, Xiao, Yajuan, Yi, Frank, Yu, Tian, Zhou, Jingsong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855744/
https://ncbi.nlm.nih.gov/pubmed/24324755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082112
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