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Defective Mitochondrial Dynamics Is an Early Event in Skeletal Muscle of an Amyotrophic Lateral Sclerosis Mouse Model

Mitochondria are dynamic organelles that constantly undergo fusion and fission to maintain their normal functionality. Impairment of mitochondrial dynamics is implicated in various neurodegenerative disorders. Amyotrophic lateral sclerosis (ALS) is an adult-onset neuromuscular degenerative disorder...

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Detalhes bibliográficos
Main Authors: Luo, Guo, Yi, Jianxun, Ma, Changling, Xiao, Yajuan, Yi, Frank, Yu, Tian, Zhou, Jingsong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855744/
https://ncbi.nlm.nih.gov/pubmed/24324755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082112
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