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Dysregulated mitochondrial Ca(2+) and ROS signaling in skeletal muscle of ALS mouse model

Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized by motor neuron loss and prominent skeletal muscle wasting. Despite more than one hundred years of research efforts, the pathogenic mechanisms underlying neuromuscular degeneration in ALS remain elusive. While t...

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Bibliographic Details
Published in:Arch Biochem Biophys
Main Authors: Zhou, Jingsong, Li, Ang, Li, Xuejun, Yi, Jianxun
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506190/
https://ncbi.nlm.nih.gov/pubmed/30682329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2019.01.024
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