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Peroxisome proliferator-activated receptor-α expression induces alterations in cardiac myofilaments in a pressure-overload model of hypertrophy

Although alterations in fatty acid (FA) metabolism have been shown to have a negative impact on contractility of the hypertrophied heart, the targets of action remain elusive. In this study we compared the function of skinned fiber bundles from transgenic (Tg) mice that overexpress a relatively low...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Heart Circ Physiol
Prif Awduron: Karam, Chehade N., Warren, Chad M., Henze, Marcus, Banke, Natasha H., Lewandowski, E. Douglas, Solaro, R. John
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407160/
https://ncbi.nlm.nih.gov/pubmed/28130336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00469.2016
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