Peroxisome proliferator-activated receptor-α expression induces alterations in cardiac myofilaments in a pressure-overload model of hypertrophy

Although alterations in fatty acid (FA) metabolism have been shown to have a negative impact on contractility of the hypertrophied heart, the targets of action remain elusive. In this study we compared the function of skinned fiber bundles from transgenic (Tg) mice that overexpress a relatively low...

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Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: Karam, Chehade N., Warren, Chad M., Henze, Marcus, Banke, Natasha H., Lewandowski, E. Douglas, Solaro, R. John
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407160/
https://ncbi.nlm.nih.gov/pubmed/28130336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00469.2016
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