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Peroxisome proliferator-activated receptor-α expression induces alterations in cardiac myofilaments in a pressure-overload model of hypertrophy

Although alterations in fatty acid (FA) metabolism have been shown to have a negative impact on contractility of the hypertrophied heart, the targets of action remain elusive. In this study we compared the function of skinned fiber bundles from transgenic (Tg) mice that overexpress a relatively low...

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Bibliografski detalji
Izdano u:Am J Physiol Heart Circ Physiol
Glavni autori: Karam, Chehade N., Warren, Chad M., Henze, Marcus, Banke, Natasha H., Lewandowski, E. Douglas, Solaro, R. John
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407160/
https://ncbi.nlm.nih.gov/pubmed/28130336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00469.2016
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