Whole-brain radiotherapy in patients with brain metastases from melanoma

por de la Fuente, Macarena, Beal, Kathryn, Carvajal, Richard, Kaley, Thomas J
Publicado en CNS Oncol (2014)

Radiographic patterns of recurrence and pathologic correlation in malignant gliomas treated with bevacizumab

por Thomas, Alissa, Rosenblum, Marc, Karimi, Sasan, DeAngelis, Lisa M, Omuro, Antonio, Kaley, Thomas J
Publicado en CNS Oncol (2018)

Bevacizumab in high-grade glioma patients following intraparenchymal hemorrhage

por Lin, Xuling, Daras, Mariza, Pentsova, Elena, Nolan, Craig P., Gavrilovic, Igor T., DeAngelis, Lisa M., Kaley, Thomas J.
Publicado en Neurooncol Pract (2017)

Phase I Study of RO4929097 with Bevacizumab in Patients with Recurrent Malignant Glioma

por Pan, Edward, Supko, Jeffrey G., Kaley, Thomas J., Butowski, Nicholas A., Cloughesy, Timothy, Jung, Jinkyu, Desideri, Serena, Grossman, Stuart, Ye, Xiaobu, Park, Deric M.
Publicado en J Neurooncol (2016)

Phase II trial of an AKT inhibitor (perifosine) for recurrent glioblastoma

por Kaley, Thomas J., Panageas, Katherine S., Mellinghoff, Ingo K., Nolan, Craig, Gavrilovic, Igor T., DeAngelis, Lisa M., Abrey, Lauren E., Holland, Eric C., Lassman, Andrew B.
Publicado en J Neurooncol (2019)

Genomic Heterogeneity Underlies Mixed Response to Tropomyosin Receptor Kinase Inhibition in Recurrent Glioma

por Schram, Alison M., Jonsson, Philip, Drilon, Alexander, Bale, Tejus A., Hechtman, Jaclyn F., Benayed, Ryma, Hanusch, Bethany, Young, Robert J., Grommes, Christian, Ku, Nora, Kaley, Thomas J., Hyman, David M., Taylor, Barry S.
Publicado en JCO Precis Oncol (2018)

A phase I study of cediranib in combination with cilengitide in patients with recurrent glioblastoma

por Gerstner, Elizabeth R., Ye, Xiaobu, Duda, Dan G., Levine, Michael A., Mikkelsen, Tom, Kaley, Thomas J., Olson, Jeffrey J., Nabors, Burt L., Ahluwalia, Manmeet S., Wen, Patrick Y., Jain, Rakesh K., Batchelor, Tracy T., Grossman, Stuart
Publicado en Neuro Oncol (2015)

Phase I clinical trial of temsirolimus and perifosine for recurrent glioblastoma

por Kaley, Thomas J., Panageas, Katherine S., Pentsova, Elena I., Mellinghoff, Ingo K., Nolan, Craig, Gavrilovic, Igor, DeAngelis, Lisa M., Abrey, Lauren E., Holland, Eric C., Omuro, Antonio, Lacouture, Mario E., Ludwig, Emmy, Lassman, Andrew B.
Publicado en Ann Clin Transl Neurol (2020)

R-MPV followed by high-dose chemotherapy with TBC and autologous stem-cell transplant for newly diagnosed primary CNS lymphoma

por Omuro, Antonio, Correa, Denise D., DeAngelis, Lisa M., Moskowitz, Craig H., Matasar, Matthew J., Kaley, Thomas J., Gavrilovic, Igor T., Nolan, Craig, Pentsova, Elena, Grommes, Christian C., Panageas, Katherine S., Baser, Raymond E., Faivre, Geraldine, Abrey, Lauren E., Sauter, Craig S.
Publicado en Blood (2015)

Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma

por Omuro, Antonio, Chan, Timothy A., Abrey, Lauren E., Khasraw, Mustafa, Reiner, Anne S., Kaley, Thomas J., DeAngelis, Lisa M., Lassman, Andrew B., Nolan, Craig P., Gavrilovic, Igor T., Hormigo, Adilia, Salvant, Cynthia, Heguy, Adriana, Kaufman, Andrew, Huse, Jason T., Panageas, Katherine S., Hottinger, Andreas F., Mellinghoff, Ingo
Publicado 2013

Phase II trial of sunitinib for recurrent and progressive atypical and anaplastic meningioma

por Kaley, Thomas J., Wen, Patrick, Schiff, David, Ligon, Keith, Haidar, Sam, Karimi, Sasan, Lassman, Andrew B., Nolan, Craig P., DeAngelis, Lisa M., Gavrilovic, Igor, Norden, Andrew, Drappatz, Jan, Lee, Eudocia Quant, Purow, Benjamin, Plotkin, Scott R., Batchelor, Tracy, Abrey, Lauren E., Omuro, Antonio
Publicado en Neuro Oncol (2015)

Phase 1b trial of an ibrutinib-based combination therapy in recurrent/refractory CNS lymphoma

por Grommes, Christian, Tang, Sarah S., Wolfe, Julia, Kaley, Thomas J., Daras, Mariza, Pentsova, Elena I., Piotrowski, Anna F., Stone, Jacqueline, Lin, Andrew, Nolan, Craig P., Manne, Malbora, Codega, Paolo, Campos, Carl, Viale, Agnes, Thomas, Alissa A., Berger, Michael F., Hatzoglou, Vaios, Reiner, Anne S., Panageas, Katherine S., DeAngelis, Lisa M., Mellinghoff, Ingo K.
Publicado en Blood (2019)

Phase II study of monthly pasireotide LAR (SOM230C) for recurrent or progressive meningioma

por Norden, Andrew D., Ligon, Keith L., Hammond, Samantha N., Muzikansky, Alona, Reardon, David A., Kaley, Thomas J., Batchelor, Tracy T., Plotkin, Scott R., Raizer, Jeffrey J., Wong, Eric T., Drappatz, Jan, Lesser, Glenn J., Haidar, Sam, Beroukhim, Rameen, Lee, Eudocia Q., Doherty, Lisa, Lafrankie, Debra, Gaffey, Sarah C., Gerard, Mary, Smith, Katrina H., McCluskey, Christine, Phuphanich, Surasak, Wen, Patrick Y.
Publicado en Neurology (2015)

Phase II Study of Bevacizumab, Temozolomide and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma

por Omuro, Antonio, Beal, Kathryn, Gutin, Philip, Karimi, Sasan, Correa, Denise D., Kaley, Thomas J., DeAngelis, Lisa M., Chan, Timothy A., Gavrilovic, Igor T., Nolan, Craig, Hormigo, Adilia, Lassman, Andrew B., Mellinghoff, Ingo, Grommes, Christian, Reiner, Anne S., Panageas, Katherine S., Baser, Raymond E., Tabar, Viviane, Pentsova, Elena, Sanchez, Juan, Barradas-Panchal, Renata, Zhang, Jianan, Faivre, Geraldine, Brennan, Cameron W., Abrey, Lauren E., Huse, Jason T.
Publicado en Clin Cancer Res (2014)

A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients

por Lee, Eudocia Q., Kaley, Thomas J., Duda, Dan G., Schiff, David, Lassman, Andrew B., Wong, Eric T., Mikkelsen, Tom, Purow, Benjamin W., Muzikansky, Alona, Ancukiewicz, Marek, Huse, Jason T., Ramkissoon, Shakti, Drappatz, Jan, Norden, Andrew D., Beroukhim, Rameen, Weiss, Stephanie E., Alexander, Brian M., McCluskey, Christine S., Gerard, Mary, Smith, Katrina H., Jain, Rakesh K., Batchelor, Tracy T., Ligon, Keith L., Wen, Patrick Y.
Publicado en Clin Cancer Res (2015)

Multicenter Phase IB Trial of Carboxyamidotriazole Orotate and Temozolomide for Recurrent and Newly Diagnosed Glioblastoma and Other Anaplastic Gliomas

por Omuro, Antonio, Beal, Kathryn, McNeill, Katharine, Young, Robert J., Thomas, Alissa, Lin, Xuling, Terziev, Robert, Kaley, Thomas J., DeAngelis, Lisa M., Daras, Mariza, Gavrilovic, Igor T., Mellinghoff, Ingo, Diamond, Eli L., McKeown, Andrew, Manne, Malbora, Caterfino, Andrew, Patel, Krishna, Bavisotto, Linda, Gorman, Greg, Lamson, Michael, Gutin, Philip, Tabar, Viviane, Chakravarty, Debyani, Chan, Timothy A., Brennan, Cameron W., Garrett-Mayer, Elizabeth, Karmali, Rashida A., Pentsova, Elena
Publicado en J Clin Oncol (2018)

Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma

por de la Fuente, Macarena I., Young, Robert J., Rubel, Jennifer, Rosenblum, Marc, Tisnado, Jamie, Briggs, Samuel, Arevalo-Perez, Julio, Cross, Justin R., Campos, Carl, Straley, Kimberly, Zhu, Dongwei, Dong, Chuanhui, Thomas, Alissa, Omuro, Antonio A., Nolan, Craig P., Pentsova, Elena, Kaley, Thomas J., Oh, Jung H., Noeske, Ralph, Maher, Elizabeth, Choi, Changho, Gutin, Philip H., Holodny, Andrei I., Yen, Katharine, DeAngelis, Lisa M., Mellinghoff, Ingo K., Thakur, Sunitha B.
Publicado en Neuro Oncol (2016)

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

por Cloughesy, Timothy F., Mochizuki, Aaron Y., Orpilla, Joey R., Hugo, Willy, Lee, Alexander H., Davidson, Tom B., Wang, Anthony C., Ellingson, Benjamin M., Rytlewski, Julie A., Sanders, Catherine M., Kawaguchi, Eric S., Du, Lin, Li, Gang, Yong, William H., Gaffey, Sarah C., Cohen, Adam L., Mellinghoff, Ingo K., Lee, Eudocia Q., Reardon, David A., O’Brien, Barbara J., Butowski, Nicholas A., Nghiemphu, Phioanh L., Clarke, Jennifer L., Arrillaga-Romany, Isabel C., Colman, Howard, Kaley, Thomas J., de Groot, John F., Liau, Linda M., Wen, Patrick Y., Prins, Robert M.
Publicado en Nat Med (2019)

Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma

por Grommes, Christian, Pastore, Alessandro, Palaskas, Nicolaos, Tang, Sarah S., Campos, Carl, Schartz, Derrek, Codega, Paolo, Nichol, Donna, Clark, Owen, Hsieh, Wan-Ying, Rohle, Dan, Rosenblum, Marc, Viale, Agnes, Tabar, Viviane S, Brennan, Cameron W, Gavrilovic, Igor T., Kaley, Thomas J, Nolan, Craig P, Omuro, Antonio, Pentsova, Elena, Thomas, Alissa A, Tsyvkin, Elina, Noy, Ariela, Palomba, M. Lia, Hamlin, Paul, Sauter, Craig S., Moskowitz, Craig H., Wolfe, Julia, Dogan, Ahmet, Won, Minhee, Glass, Jon, Peak, Scott, Lallana, Enrico C, Hatzoglou, Vaios, Reiner, Anne S, Gutin, Philip H, Huse, Jason T, Panageas, Katherine S, Graeber, Thomas G, Schultz, Nikolaus, DeAngelis, Lisa M, Mellinghoff, Ingo K
Publicado en Cancer Discov (2017)

Genomic correlates of disease progression and treatment response in prospectively characterized gliomas

por Jonsson, Philip, Lin, Andrew L., Young, Robert J., DiStefano, Natalie M., Hyman, David M., Li, Bob T., Berger, Michael F., Zehir, Ahmet, Ladanyi, Marc, Solit, David B., Arnold, Angela G., Stadler, Zsofia K., Mandelker, Diana, Goldberg, Michael E., Chmielecki, Juliann, Pourmaleki, Maryam, Ogilvie, Shahiba Q., Chavan, Shweta S., McKeown, Andrew T., Manne, Malbora, Hyde, Allison, Beal, Kathryn, Yang, T. Jonathan, Nolan, Craig P., Pentsova, Elena, Omuro, Antonio, Gavrilovic, Igor T., Kaley, Thomas J., Diamond, Eli L., Stone, Jacqueline B., Grommes, Christian, Boire, Adrienne, Daras, Mariza, Piotrowski, Anna F., Miller, Alexandra M., Gutin, Philip H., Chan, Timothy A., Tabar, Viviane S., Brennan, Cameron W., Rosenblum, Marc, DeAngelis, Lisa M., Mellinghoff, Ingo K., Taylor, Barry S.
Publicado en Clin Cancer Res (2019)