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A phase I study of cediranib in combination with cilengitide in patients with recurrent glioblastoma
BACKGROUND: Despite being a highly vascularized tumor, glioblastoma response to anti-vascular endothelial growth factor (VEGF) therapy is transient, possibly because of tumor co-option of preexisting blood vessels and infiltration into surrounding brain. Integrins, which are upregulated after VEGF i...
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| 出版年: | Neuro Oncol |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4578584/ https://ncbi.nlm.nih.gov/pubmed/26008604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov085 |
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