A Safety Run-in and Randomized Phase II Study of Cilengitide Combined with Chemoradiation for Newly Diagnosed Glioblastoma (NABTT 0306)

BACKGROUND: Cilengitide is a selective integrin inhibitor that is well tolerated and has demonstrated biological activity in patients with recurrent malignant glioma. The primary objectives of this randomized phase II trial were to determine safety and efficacy of cilengitide when combined with radi...

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Main Authors: Nabors, L. Burt, Mikkelsen, Tom, Hegi, Monika E., Ye, Xiaubu, Batchelor, Tracy, Lesser, Glenn, Peereboom, David, Rosenfeld, Myrna R., Olsen, Jeff, Brem, Steve, Fisher, Joy D., Grossman, Stuart A.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423527/
https://ncbi.nlm.nih.gov/pubmed/22517399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27585
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