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A Phase I and Correlative Biology Study of Cilengitide in Patients with Recurrent Malignant Glioma

PURPOSE: This multi-institutional phase I trial was designed to determine the maximum tolerated dose (MTD) of cilengitide (EMD 121974) and evaluate the use of perfusion MRI in patients with recurrent malignant glioma. PATIENTS AND METHODS: Patients received cilengitide twice weekly on a continuous b...

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Detalhes bibliográficos
Main Authors: Nabors, L. Burt, Mikkelsen, Tom, Rosenfeld, Steve, Hochberg, Fred, Akella, N. Shastry, Fisher, Joy D., Cloud, Gretchen, Zhang, Yu, Carson, Kathryn A., Wittemer, Sabine M., Colevas, A. Dimitrios, Grossman, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811028/
https://ncbi.nlm.nih.gov/pubmed/17470857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2006.06.6514
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