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Cilengitide induces autophagy-mediated cell death in glioma cells

We studied the effect of the integrin inhibitor cilengitide in glioma cells. Cilengitide induced cell detachment and decreased cell viability, and induction of autophagy followed by cell apoptosis. In addition, cilengitide decreased the cell renewal of glioma stem-like cells (GSCs). Inhibition of au...

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Bibliografische gegevens
Hoofdauteurs: Lomonaco, Stephanie L., Finniss, Susan, Xiang, Cunli, Lee, Hae Kyung, Jiang, Wei, Lemke, Nancy, Rempel, Sandra A., Mikkelsen, Tom, Brodie, Chaya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145473/
https://ncbi.nlm.nih.gov/pubmed/21788343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor073
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