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GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis

We characterized the expression and function of the endoplasmic reticulum protein GRP78 in glial tumors. GRP78 is highly expressed in glioblastomas but not in oligodendrogliomas, and its expression is inversely correlated with median patient survival. Overexpression of GRP78 in glioma cells decrease...

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Bibliografski detalji
Glavni autori: Lee, Hae Kyung, Xiang, Cunli, Cazacu, Simona, Finniss, Susan, Kazimirsky, Gila, Lemke, Nancy, Lehman, Norman L., Rempel, Sandra A., Mikkelsen, Tom, Brodie, Chaya
Format: Artigo
Jezik:Inglês
Izdano: Duke University Press 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563046/
https://ncbi.nlm.nih.gov/pubmed/18403493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-006
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