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GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis

We characterized the expression and function of the endoplasmic reticulum protein GRP78 in glial tumors. GRP78 is highly expressed in glioblastomas but not in oligodendrogliomas, and its expression is inversely correlated with median patient survival. Overexpression of GRP78 in glioma cells decrease...

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Detalhes bibliográficos
Main Authors: Lee, Hae Kyung, Xiang, Cunli, Cazacu, Simona, Finniss, Susan, Kazimirsky, Gila, Lemke, Nancy, Lehman, Norman L., Rempel, Sandra A., Mikkelsen, Tom, Brodie, Chaya
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563046/
https://ncbi.nlm.nih.gov/pubmed/18403493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-006
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