GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis

We characterized the expression and function of the endoplasmic reticulum protein GRP78 in glial tumors. GRP78 is highly expressed in glioblastomas but not in oligodendrogliomas, and its expression is inversely correlated with median patient survival. Overexpression of GRP78 in glioma cells decrease...

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Autori principali: Lee, Hae Kyung, Xiang, Cunli, Cazacu, Simona, Finniss, Susan, Kazimirsky, Gila, Lemke, Nancy, Lehman, Norman L., Rempel, Sandra A., Mikkelsen, Tom, Brodie, Chaya
Natura: Artigo
Lingua:Inglês
Pubblicazione: Duke University Press 2008
Soggetti:
Rapid Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563046/
https://ncbi.nlm.nih.gov/pubmed/18403493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-006
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