TRAIL conjugated to nanoparticles exhibits increased anti-tumor activities in glioma cells and glioma stem cells in vitro and in vivo

Glioblastomas (GBM) are characterized by resistance to chemotherapy and radiotherapy, and therefore, alternative therapeutic approaches are needed. TRAIL induces apoptosis in cancer but not in normal cells and is considered to be a promising anti-tumor agent. However, its short in vivo half-life and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Perlstein, Benny, Finniss, Susan A., Miller, Cathie, Okhrimenko, Hana, Kazimirsky, Gila, Cazacu, Simona, Lee, Hae Kyung, Lemke, Nancy, Brodie, Shlomit, Umansky, Felix, Rempel, Sandra A., Rosenblum, Mark, Mikklesen, Tom, Margel, Shlomo, Brodie, Chaya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534416/
https://ncbi.nlm.nih.gov/pubmed/23144078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos248
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados