TRAIL conjugated to nanoparticles exhibits increased anti-tumor activities in glioma cells and glioma stem cells in vitro and in vivo

Glioblastomas (GBM) are characterized by resistance to chemotherapy and radiotherapy, and therefore, alternative therapeutic approaches are needed. TRAIL induces apoptosis in cancer but not in normal cells and is considered to be a promising anti-tumor agent. However, its short in vivo half-life and...

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Dades bibliogràfiques
Autors principals: Perlstein, Benny, Finniss, Susan A., Miller, Cathie, Okhrimenko, Hana, Kazimirsky, Gila, Cazacu, Simona, Lee, Hae Kyung, Lemke, Nancy, Brodie, Shlomit, Umansky, Felix, Rempel, Sandra A., Rosenblum, Mark, Mikklesen, Tom, Margel, Shlomo, Brodie, Chaya
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Basic and Translational Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534416/
https://ncbi.nlm.nih.gov/pubmed/23144078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos248
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