Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal

MicroRNAs (miRNAs) have emerged as potential cancer therapeutics; however, their clinical use is hindered by lack of effective delivery mechanisms to tumor sites. Mesenchymal stem cells (MSCs) have been shown to migrate to experimental glioma and to exert anti-tumor effects by delivering cytotoxic c...

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Autors principals: Lee, Hae Kyung, Finniss, Susan, Cazacu, Simona, Bucris, Efrat, Ziv-Av, Amotz, Xiang, Cunli, Bobbitt, Kevin, Rempel, Sandra A., Hasselbach, Laura, Mikkelsen, Tom, Slavin, Shimon, Brodie, Chaya
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2013
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712579/
https://ncbi.nlm.nih.gov/pubmed/23548312
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